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. 2008 Feb 6;28(6):1421–1426. doi: 10.1523/JNEUROSCI.4751-07.2008

Table 1.

Phasic inhibitory currents recorded in different neurons from WT and Gabra5/Gabrd−/−

WT
Gabra5/Gabrd−/−
CA1 PC CA3 PC DGGC CA1 PC CA3 PC DGGC
sIPSCs sEPSCs sIPSCs sEPSCs sIPSCs sEPSCs sIPSCs sEPSCs sIPSCs sEPSCs sIPSCs sEPSCs
Imean (pA/sec) 2.25 ± 0.36 0.37 ± 0.04 11.8 ± 2.0 1.86 ± 0.59 1.96 ± 0.72 0.32 ± 0.03 2.04 ± 0.47 0.42 ± 0.05 17.2 ± 2.98 2.19 ± 0.40 1.17 ± 0.41 0.32 ± 0.08
Frequency (Hz) 20.8 ± 3.04 3.13 ± 0.71 39.0 ± 3.12 15.1 ± 0.82 12.8 ± 3.67 4.84 ± 1.10 20.9 ± 3.06 4.35 ± 0.64 40.0 ± 2.17 19.0 ± 2.76 10.6 ± 2.45 2.81 ± 0.58
Peak amplitude (pA) 15.8 ± 0.40 14.9 ± 1.04 32.6 ± 3.04 19.5 ± 3.10 18.4 ± 1.86 12.2 ± 0.28 16.2 ± 0.87 14.7 ± 1.59 41.9 ± 5.59 20.1 ± 1.55 16.5 ± 1.38 11.6 ± 0.94
RT10–90 (ms) 0.78 ± 0.03 0.81 ± 0.03 1.72 ± 0.09 1.15 ± 0.06 1.17 ± 0.07 0.88 ± 0.05 0.69 ± 0.03 0.67 ± 0.07 1.76 ± 0.08 1.22 ± 0.08 1.21 ± 0.08 0.95 ± 0.03
Tw (ms) 8.45 ± 0.14 5.53 ± 0.36 9.82 ± 0.39 6.27 ± 0.23 8.05 ± 0.29 4.92 ± 0.14 8.22 ± 19 5.62 ± 0.17 10.7 ± 0.38 6.65 ± 0.19 8.2 ± 0.34 4.78 ± 0.24
n 5 5 8 8 7 7

Imean, sIPSCs, and sEPSCs recorded in aCSF with a low Cl pipette solution.