Table 2.
Tonic inhibitory current recorded in the different neurons and genotypes
| Tonic current (pA) | CA1 PC | n | CA3 PC | n | DGGC | n | ML interneurons | n |
|---|---|---|---|---|---|---|---|---|
| WT | 38.9 ± 5.10 | 12 | 30.1 ± 5.28 | 8 | 22.0 ± 5.33 | 5 | 12.2 ± 1.68 | 17 |
| Gabra5−/− | 23.1 ± 1.75 | 17 | 16.1 ± 2.89 | 4 | 20.3 ± 4.03 | 5 | 13.0 ± 2.79 | 5 |
| Gabrd−/− | 36.2 ± 2.17 | 5 | 30.9 ± 4.40 | 5 | 6.59 ± 1.42 | 6 | 12.0 ± 3.46 | 7 |
| Gabra5/Gabrd−/− | 1.47 ± 0.59 | 6 | 3.12 ± 1.74 | 4 | 1.56 ± 0.21 | 5 | 1.83 ± 1.75 | 5 |
| WT + 50 nm L-655,708 | 11.3 ± 3.17 | 6 | nd | nd | 15.8 ± 4.1 | 5 | nd | nd |
| WT + 200 nm L-655,708 | 12.6 ± 3.56 | 6 | nd | nd | nd | nd | nd | nd |
| Gabrd−/−+ 50 nm L-655,708 | 13.2 ± 1.37 | 5 | nd | nd | 1.84 ± 0.69 | 8 | nd | nd |
Imean, sIPSCs, and sEPSCs recorded in aCSF with a low Cl− pipette solution.nd, Not determined