Cortical topography surrounding the ratunculus in primary somatosensory cortex (a). VC, Visual cortex; fl, forelimb; hl, hindlimb; SI, primary somatosensory cortex; MC, motor cortex; cg, cingulate cortex; OB, bulbus olfactorius; RAG, retrosplenial cortex; TE, temporal cortex; CR, cerebral cortex; SII, secondary somatosensory cortex; Ins, insular cortex; PIR, piriform cortex. Classification of the zones attributable to the specific changes of the transmitters and proteins immediately after two hours of ICMS and overlay these to the cortical representation (b). FP, Forepaw; HP, hindpaw; IZ, inhibition zone; UZ, unresponsive zone.