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. 2008 Nov 19;28(47):12570–12580. doi: 10.1523/JNEUROSCI.4048-08.2008

Figure 5.

Figure 5.

Reduced expression of GABAergic markers in the ATRX-null forebrain. A, Real-time reverse transcriptase PCR of GABAergic markers in forebrain tissue isolated from E13.5 and P0.5 control and AtrxFoxg1Cre littermate embryos (n = 3). B, Immunofluorescence detection of Npy in the ventral telencephalon at E13.5 and E16.5 shows reduced staining levels in the ATRX-null embryos. Npy, Neuropeptide Y; Sst, somatostatin; Dlx5, distal-less homeobox 5; Gbx2, gastrulation brain homeobox 2; Lhx6, LIM homeobox protein 6; Cck, cholecystokinin. E13.5: Scale bar, 200 μm; E16.5: Scale bar, 150 μm.