Figure 1.

Effects of hRANTES on the [³H]d-ASP release from human neocortical synaptosomes. A, Time course of [³H]d-ASP release. Dotted line, Spontaneous release. Gray square, 1 nm hRANTES-evoked [³H]d-ASP release. Results are expressed as percentages of the first superfusion fraction collected (b1). Data are means ± SEM of three experiments run in triplicate (3 superfusion chambers for each experimental condition). B, Concentration–effect relationship of hRANTES on the release of [³H]d-ASP from human neocortical synaptosomes. Results are expressed as percentage of induced overflow. Data are means of four experiments run in triplicate. *p < 0.05 versus control.