Figure 7.

Western blot analysis of CCR1, CCR3 and CCR5 proteins in detergent-soluble synaptosomal membrane fractions. Western blot compares the CCR1, the CCR3, and the CCR5 immunoreactivities in a fraction enriched in human neocortical synaptosomal membranes. Anti-Stx-1A, anti-Syph, and anti-GFAP were used as selective markers of the neuronal and glial components to evaluate the purity of our preparations. Twenty-five micrograms of proteins were applied to the SDS PAGE gel. Protein weights are in kilodaltons. The blot in the figure is representative of four blots from synaptosomal preparations obtained from different patients on different days.