Figure 8.

Effects of anti-CCR1, CCR3, and CCR5 antibodies on the hRANTES-induced changes in the spontaneous and the K⁺-evoked release of [³H]d-ASP from human neocortical synaptosomes. A, Effects on the spontaneous release of [³H]d-ASP in absence (white bar) or in presence (gray bar) of hRANTES. B, Effects on the release of [³H]d-ASP evoked by 12 mm K⁺ in absence (white bar) or in presence (gray bar) of hRANTES. Results are expressed as percentage of induced overflow. Data are means ± SEM from 10 experiments run in triplicate. *p < 0.05 versus respective control; ^# p < 0.05 versus 1 nm hRANTES.