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. 2008 Feb 27;28(9):1997–2005. doi: 10.1523/JNEUROSCI.4231-07.2008

Figure 7.

Figure 7.

Some accumulating vesicles in the mutant dynactin p150 Glued mice are components of the ER and Golgi. A–C, Ventral spinal cord of nontransgenic (A) and transgenic (B) mice labeled with GRP94. There is an accumulation of GRP94 labeled structures within a number of the motor neurons. C, Shows FLAG staining in the motor neurons of mutant p150Glued mice. D–F, Ventral spinal cord of nontransgenic (D) and transgenic (E) mice labeled with p115. There is an accumulation of p115 labeled structures in the majority of motor neuron cell bodies in the transgenic mice. F, Shows FLAG staining in the motor neurons of mutant p150Glued mice.