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Effect of stress on ATF2, ATF3, and ATF4 mRNA expression in striatum. a–c, Time course of ATF2, ATF3, and ATF4 mRNA levels by acute restraint stress. Points represent mean ± SEM relative induction from nonstressed controls (n = 4). d–f, Effect of acute and repeated restraint stress on ATF2, ATF3, and ATF4 mRNA levels compared with nonstressed controls (Ctrl) at 1 h after the last stress. Asterisks denote statistical difference (*p < 0.05) from nonstressed controls.
