HSV-mediated ATF3 overexpression in nucleus accumbens. Double fluorescent immunohistochemistry demonstrating coexpression of GFP (a) and ATF3 (b) in rat nucleus accumbens, along with a merged image (c). Coexpression of GFP and ATF3 was >95%. Similar results were obtained for ATF2 and ATF4 (data not shown). d, Representative injection site and expression pattern. ac, Anterior commissure; AcbC, nucleus accumbens core; AcbSh, shell.