Figure 5.

Physiological and anatomical properties of an Aβ polymodal nociceptor. Relatively short-duration AHP (A) was atypical for myelinated nociceptors (compare with Figs. 3, 6). Furthermore, this afferent was relatively sensitive to low mechanical forces (B; bars from left to right signify 0.07, 0.16, and 0.35 mN). Sensitization to repeated heating is evident in C. D, E, Note that arbors extended dorsally into ventral SG. Postnatal age, CV, mechanical threshold, and heat threshold (first exposure) were 47 d, 16 m/s, 0.07 mN, and 53°C, respectively. Calibration: 20 mV; A, 10 ms; B, 100 ms; C, 10 s. Scale bar, 100 μm.