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Western blot analysis for proteins involved in mitochondrial biogenesis in subcortex of eNOS−/− mice exposed to HH. A, Representative Western blots of PGC-1α expression and CREB phosphorylation in nuclear extracts of brains of control eNOS−/− mice and eNOS−/− mice after hypoxia (6 h). B, Histogram shows densitometry values for PGC-1α and CREB relative to tubulin, expressed as means ± SEM of four animals at each group (*p < 0.05 compared with control).
