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. 2019 Jul 25;10:1626. doi: 10.3389/fmicb.2019.01626

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Copyright © 2019 van Vugt, Arts and Geurts.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Examples of the application of antibiotic loaded Polymethylmethacrylate in the orthopedic practice. In figure on the left side, solely antibiotic loaded PMMA-beads are used in treatment of infected TKP. In the middle beads and a (hand-molded) spacer are used for treatment of an infected TKP. In the figure on the right side, PMMA-beads are used in treatment of chronic osteomyelitis.