Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 1;9:11187. doi: 10.1038/s41598-019-47593-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Correlation of ΔΨ_m and YAP/TAZ nuclear translocation in micropatterns. (A) Schematics of the three micropattern cultures used in this experiment; (B) TMRM staining of ΔΨ_m (scale bar: 500 μm) and YAP/TAZ immunostaining (scale bar: 25 μm) in the three micropatterns on day 4; (C) Quantification of cancer cells with nuclear YAP/TAZ localization at the center and edge of the µTSA (n.s.: not significant; ****p < 0.0001 by ordinary one-way ANOVA); Representative dataset from N = 3 independent experiments. (D) Linear regression of YAP/TAZ nuclear localization and TMRM fluorescence in cancer cells in the monoculture and co-culture µTSA. Three locations (center, edge and approximately 700 μm away from the edge) were taken from the monoculture µTSA and two locations (center and edge) from the co-culture. (Representative dataset, N = 2 independent experiments; p-value: zero-slope hypothesis in linear regression).