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. 2019 Aug 1;5:12. doi: 10.1038/s41537-019-0080-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Correlations between change in PANSS score (−100% indicates full symptomatic improvement, whereas 0% denotes no change in symptoms) and change in thalamic Glx levels over 9 months (negative values indicate reduction in thalamic Glx levels, whereas positive values indicate increase in thalamic Glx). a Significant positive correlation between the percentage change in Glx levels in the thalamus and the percentage change in PANSS positive score (r = .493, P = 0.023), (b) PANSS total score (r = .501, P = 0.018) and (c) PANSS general score (r = .446, P = 0.037), between baseline and 9 months. d No significant correlation for the percentage change in PANSS negative score