Table 2.
DEGs and molecular signature related to heme metabolism in S1 dataset
| Group | D0S | D0NS | D7S | D7NS |
|---|---|---|---|---|
| N° DEGs | 255 | 193 | 187 | 114 |
| ↑/↓ | ↑121 and ↓134 | ↑137 and ↓56 | ↑99 and ↓88 | ↑71 and ↓43 |
| FDR | 2.11E−07 | NEa | 9.96E−14 | 1.84E−03 |
| Enrichment position | 3rd of 25 | NEa | 1st of 12 | 3rd of 13 |
| N° Genes | 11 | 1 | 15 | 5 |
| ↑ AHSP | ↑H1F0 | ↑AHSP | ↑ ALAS2 | |
| ↑ ALAS2 | ↑ALAS2 | ↑ EPB42 | ||
| ↑ CA1 | ↑CA1 | ↑ HBD | ||
| ↑ EPB42 | ↑EPB42 | ↑ SELENBP1 | ||
| ↑ GYPA | ↑ FAM46C | ↑ SLC4A1 | ||
| ↑ HBD | ↑ GYPA | |||
| ↑ RBM5 | ↑ HBD | |||
| ↑ RHCE | ↑ RAP1GAP | |||
| ↑ SELENBP1 | ↑ RHCE | |||
| ↑ SLC25A37 | ↑ SELENBP1 | |||
| ↑ SLC4A1 | ↑ SLC25A37 | |||
| ↑ SLC4A1 | ||||
| ↑ SLC6A8 | ||||
| ↑ SPTA1 | ||||
| ↑ TNS1 |
D0S = Day 0 surviving group, D0NS = Day 0 Non-surviving group, D7S = Day 7 surviving group and D7NS = Day 7 Non-surviving group; ↑ Upregulated genes, and ↓ downregulated genes
aNE not enriched (the pathway was not found within the established parameters due to the small amount of genes related to it in this group)