. 2019 Aug 1;5:26. doi: 10.1038/s41540-019-0105-4

Table 3.

DEGs and molecular signature related to heme metabolism in S2 dataset

Group	D1S	D1NS	D3S	D3NS	D5S	D5NS
N° DEGs	224	274	159	268	173	184
↑/↓	↑132 and ↓92	↑144 and ↓130	↑101 and ↓58	↑158 and ↓110	↑109 and ↓64	↑111 and ↓73
FDR	NE^a	NE^a	5.10E−04	NE^a	1.07E−07	NE^a
Enrichment position	NE^a	NE^a	7th of 18	NE^a	2nd de 18	NE^a
N° Genes	3	3	6	4	10	3
	↑ALAS2	↑ALAS2	↑AHSP	↑FAM46C	↑AHSP	↑FAM46C
	↑CA1	↑FAM46C	↑ALAS2	↑HBQ1	↑ALAS2	↑HBQ1
	↑E2F2	↑HBQ1	↑CA1	↑NFE2	↑CA1	↑SLC22A4
			↑FAM46C	↑RAP1GAP	↑FAM46C
			↑HBD		↑GYPE
			↑RAP1GAP		↑HBD
					↑HBQ1
					↑OSBP2
					↑RAP1GAP
					↑XK

D1S = Day 1 surviving group, D1NS = Day 1 Non-surviving group, D3S = Day 3 surviving group, D3NS = Day 3 Non-surviving group, D5S = Day 5 surviving group and D5NS = Day 5 Non-surviving group; ↑ Upregulated genes and ↓ downregulated genes

^aNE not enriched (the pathway was not found within the established parameters due to the small amount of genes related to it in this group)