Table 1.

Differential expression of EV-miRNAs in HCT116 compared to SW480 under RAPA and CsA treatment.

miR-ID	HCT116				SW480				RT-PCR Validation
	RAPA vs Untr		CsA vs Untr		RAPA vs Untr		CsA vs Untr
	FC	P	FC	P	FC	P	FC	P
miR-6796-5p	6.978	0.001	−2.204	0.003	1.089	0.615	−1.483	0.125	Ø
miR-6746-5p	2.084	0.030	−2.024	0.005	1.423	0.034	−1.626	0.023	√
miR-6787-5p	4.166	0.035	−3.292	0.022	1.212	0.215	1.024	0.920	√
miR-6776-5p	4.126	0.017	−4.276	0.004	1.274	0.124	−1.038	0.757	Ø
miR-6127	4.457	0.007	−3.486	0.004	1.161	0.232	−1.381	0.056	√
miR-6846-5p	2.345	0.014	−2.309	0.009	1.111	0.460	−1.326	0.053	Ø

Target genes had cumulative weighted context++ scores from the top to zero.

FC = fold change.

*P < 0.01 versus Untr (untreated).

Ø Negative RT-PCR Validation.

√ Positive RT-PCR Validation.