TABLE 2.
Baseline biochemical and radiological characteristics of the AA-DHS cohort
| Variables | AA-DHS Cohort | ||||||
| Full Sample | N | Living | N | Deceased | N | P | |
| Fasting glucose (mmol/l) | 7.41 (5.94, 9.71) | 540 | 7.38 (5.94, 9.66) | 459 | 7.60 (6.16, 10.32) | 81 | 0.3955 |
| GHb (%) | 7.7 (6.6, 9.1) | 531 | 7.7 (6.6, 9.1) | 453 | 7.7 (6.7, 9.3) | 78 | 0.9787 |
| Serum creatinine μmol/l | 80.0 (70.7, 97.2) | 540 | 79.6 (70.7, 97.2) | 459 | 88.4 (70.7, 97.2) | 81 | 0.0060 |
| HDL cholesterol (mmol/l) | 1.19 (0.98, 1.40) | 540 | 1.17 (0.98,1.40) | 459 | 1.19 (0.98, 1.42) | 81 | 0.6909 |
| LDL cholesterol (mmol/l) | 2.67 (2.15, 3.39) | 529 | 2.72 (2.20, 3.44) | 449 | 2.42 (1.83, 3.03) | 80 | 0.0019 |
| Triglycerides (mmol/l) | 1.18 (0.87, 1.65) | 540 | 1.18 (0.87, 1.65) | 459 | 1.13 (0.86, 1.56) | 81 | 0.4587 |
| Coronary artery CP mass (mg Ca+) | 26.5 (0.0, 346.5) | 463 | 17.5 (0.0, 256) | 398 | 184 (7.0, 854) | 65 | 0.0002 |
| Coronary artery CP >10 mg Ca+ (%) | 56.6 | 463 | 54.0 | 398 | 72.3 | 65 | 0.0058 |
| Carotid artery CP mass (mg Ca+) | 4.0 (0.0, 104) | 537 | 2.5 (0.0, 87.0) | 458 | 52.5 (0.0, 284.5) | 79 | 0.0003 |
| Carotid artery CP >10 mg Ca+ (%) | 45.6 | 537 | 42.6 | 458 | 63.3 | 79 | 0.0006 |
| Aorta CP mass (mg Ca+) | 1,049 (28, 6,368) | 535 | 839 (17, 5575) | 456 | 2663 (400, 11764) | 79 | 0.0003 |
| Aorta CP >10 mg Ca+ (%) | 78.5 | 535 | 77.0 | 456 | 87.3 | 79 | 0.0384 |
| Vascular beds with CP, N | 2 (1, 3) | 540 | 2 (1, 2) | 460 | 2 (1, 3) | 80 | 0.0050 |
| eGFR (ml/min/1.73 m2) | 91.3 (76.1, 111.3) | 540 | 91.4 (76.6, 113.0) | 459 | 88.8 (70.8, 104.0) | 81 | 0.0765 |
| eGFR <60 ml/min/1.73 m2 (%) | 9.6 | 540 | 8.5 | 459 | 16.0 | 81 | 0.0336 |
| UACR (mg/mmol) | 1.47 (0.47, 6.01) | 535 | 1.24 (0.46, 4.97) | 455 | 4.64 (0.64, 15.0) | 80 | 0.0002 |
| UACR >3.39 mg/mmol (%) | 36.3 | 535 | 32.5 | 455 | 57.5 | 80 | <0.0001 |
| Plasma apoM (μM) | 0.76 (0.64, 0.89) | 544 | 0.78 (0.65, 0.91) | 463 | 0.68 (0.53, 0.80) | 81 | <0.0001 |
| HDL apoM (μM) | 0.42 (0.31, 0.52) | 544 | 0.42 (0.33, 0.53) | 464 | 0.34 (0.22, 0.48) | 80 | 0.0008 |
| S1P | 0.81 (0.69, 0.93) | 544 | 0.83 (0.70, 0.94) | 463 | 0.74 (0.63, 0.87) | 81 | 0.0003 |
Data are expressed as median (25th percentile, 75th percentile) for continuous variables or percent. P for comparisons of living versus deceased participants. CP, calcified plaque.