Skeletal muscle lipidome. Sphingolipid (A), cholesterol (B), glycerolipid (C), and phospholipid (D) content in the quadriceps of WT (white bar) and BLAJ (black bar) mice presented as absolute units relative to protein mass. E: PC-PE ratio. F: Abundance of the lipid classes/subclasses for BLAJ muscles expressed as a percentage change relative to WT. CE, cholesteryl ester; Cer, ceramide; COH, cholesterol; dhCer, dihydroceramide; GM3, GM3 ganglioside; Hex1Cer, monohexosylceramide; Hex2Cer, dihexosylceramide; Hex3Cer, trihexosylceramide; LPC, lysophosphatidylcholine; LPC(O), lysoalkylphosphatidylcholine; LPC(P), lysoalkenylphosphatidylcholine; LPE, lysophosphatidylethanolamine; LPE(P), lysoalkenylphosphatidylethanolamine; LPI, lysophosphatidylinositol; PC(O), alkylphosphatidylcholine; PC(P), alkenylphosphatidylcholine; PE(O), alkylphosphatidylethanolamine; PE(P), alkenylphosphatidylethanolamine; PI, phosphatidylinositol; PS, phosphatidylserine. Data are means ± SEMs, n = 8 WT and n = 8 BLAJ mice. *P < 0.05 versus WT as assessed by two-tailed unpaired t-test.