TABLE 2.

Stability of endocannabinoids in plasma, assessed by incubation experiments of untreated, acidified, and stabilized plasma samples

All incubations were performed at 25°C. To assess the stability of deuterated IS, samples were spiked prior to incubation (n = 3). To quantify endogenous metabolite levels, IS was spiked after incubation (n = 3). Statistical testing relative to time point zero was performed with one-way ANOVA with repeated measures, with Bonferroni´s post hoc correction. Samples with P < 0.05 are shown in dashed boxes; those with P < 0.01 are highlighted in a full box.