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. 2007 Jan 10;27(2):279–288. doi: 10.1523/JNEUROSCI.3370-06.2007

Figure 2.

Figure 2.

Expression of activated Ras in peripheral glia increases perineurial glial growth. A, TEMs of cross sections from representative peripheral nerves of the indicated genotypes. The gli>Ras+ nerve is the same nerve cross section shown Figure 1A. B, Perineurial glial thickness (y-axis) from the indicated genotypes (x-axis). Means ± SEMs are indicated. One-way ANOVA and Scheffé's tests for multiple comparisons showed the following statistically significant differences, denoted by asterisks: gli>RasV12(strong) (2.08 ± 0.082 μm; n = 78), gli>RasV12(weak) (2.37 ± 0.236 μm; n = 20), gli>RasV12(strong), RasV12(weak) (2.28 ± 0.130 μm; n = 56), and gli>RasV12(strong), GFP (2.57 ± 0.17 μm; n = 43) versus gli>Ras+ (1.48 ± 0.048 μm; n = 99), gli–Gal4/+ (1.46 ± 0.057 μm; n = 60), UAS–RasV12(strong)/+ (1.37 ± 0.068 μm; n = 45), and UAS-RasV12(weak)/+ (1.53 ± 0.088 μm; n = 22). For all such tests, p < 0.0001.