Figure 2.

Locomotor recovery after spinal contusion injury in OPN-deficient and WT mice. The BMS scores in KO and WT mice (n = 8 per each group) were determined at 42 d after injury. The BMS scores were consistently greater in WT than KO for 42 d. Repeated-measures ANOVA followed by post hoc test showed that KO mice had significantly worse BMS score than WT (p < 0.05). Post hoc tests at each time point showed statistical significance at 14 and 42 d after injury (*p < 0.05). Although the scores of WT mice increased for 42 d, the scores of KO mice at 28 d were decreased at 42 d. Error bars illustrate the SEM.