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Hdh (CAG)150 HOM mice display clasping and escape behaviors. a, HOM mice displayed clasping behavior as early as 20 weeks, and the number of mice presenting this behavior increased at 70 and 100 weeks. Clasping was not observed at the 40 or 50 week time points. b, Before motor deficits, Hdh (CAG)150 mice exhibited escape behavior at 20 and 40 weeks. A larger percentage of Hdh (CAG)150 mice were able to escape compared with WT controls at both time points.
