Table 3.
Genes significantly altered at 60, 90, and 120 d in motorneurons expressing the WT SOD1
| Probe identification | Gene | Fold change |
|---|---|---|
| 60 d | ||
| 1416345_at | Translocase of inner mitochondrial membrane 8 homolog a (yeast) | 2.05 |
| 1416500_at | SAC1 (supressor of actin mutations 1, homolog)-like (Saccharomyces cerevisiae) | 2.34 |
| 1424455_at | G-protein-coupled receptor-associated sorting protein 1 | −2.5 |
| 1424918_at | TBC1 domain family, member 19 | 3.01 |
| 1425468_at | Proteolipid protein (myelin) 1 | 2.12 |
| 1427923_at | Zinc metalloproteinase, STE24 homolog (S. cerevisiae) | 2.65 |
| 1435898_x_at | GDP dissociation inhibitor 3 | 2.54 |
| 1437468_x_at | F-box and WD-40 domain protein 11 | −2.07 |
| 1452141_a_at | Selenoprotein P, plasma, 1 | 2.55 |
| 1454697_at | Translocation protein 1 | −2.54 |
| 1455422_x_at | Septin 4 | 2.76 |
| 1456015_x_at | 2.87 | |
| 1456360_at | RIKEN cDNA 1700022C02 gene | 2.45 |
| 90 d | ||
| 1416852_a_at | Neurochondrin | −2.04 |
| 1419738_a_at | Tropomyosin 2 β | −2.11 |
| 1422156_a_at | Ribosomal protein S2 | −2.16 |
| 1449702_at | Zinc finger AN1-type domain 2A | −2.13 |
| 120 d | ||
| 1449434_at | Carbonic anhydrase 3 | 6.87 |
| 1427445_a_at | Titin | 2.45 |
| 1417464_at | Troponin C2 fast | 3.12 |
| 1427026_at | Myosin heavy polypeptide 4 skeletal muscle | 8.90 |
| 1427520_a_at | Myosin heavy polypeptide 1 skeletal muscle adult | 8.29 |
| 1434326_x_at | Coronin actin-binding protein 2B | 2.35 |
| 1437044_a_at | Glucosidase β acid | 2.32 |
| 1439429_x_at | Deltex 2 homolog (Drosophila) | 2.38 |
| 1434893_at | ATPase Na+/K+ transporting α2 polypeptide mRNA (cDNA clone MGC:36347 IMAGE:4955003) | −2.13 |
| 1428289_at | Kruppel-like factor 9 | −2.01 |
| 1433785_at | Myelin-associated oligodendrocytic basic protein | −3.08 |
| 1456084_x_at | Fibromodulin | −2.36 |
| 1424635_at | Eukaryotic translation elongation factor 1 α 1 | −2.72 |
| 1426195_a_at | Cystatin C | −2.03 |
| 1416454_s_at | Actin α2 smooth muscle aorta | −2.11 |
| 1455546_s_at | Splicing factor 3a subunit 2 | 2.36 |