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CISH signals with a chromosome 17 probe in lymphocytes, HeLa cells and neurons of the entorhinal cortex in one advanced case of AD. A, Two spots are present in 99% of all lymphocytes. B, Proliferating HeLa cells show either two or four spots, indicating a diploid and tetraploid DNA amount. C–F, Neurons in an advanced case of AD showing one, two, three, or four spots (arrows). Scale bars, 10 μm.
