Figure 3.

Effects of combined neonatal iron and systemic paraquat administration on dopaminergic neurodegeneration in vivo with increasing age. A, Photomicrographs of SNpc TH-immunostained sections from 24-month-old mice. Original magnification, 10×. B, Quantitative stereological analysis of the number of TH-stained profiles from saline plus saline (purple bars), neonatal iron fed plus saline (green bars), saline plus paraquat (yellow bars), and neonatal iron plus paraquat (black bars). Error bars indicate mean ± SEM. n = 4–5. ^#p < 0.01, significantly from saline plus saline group;*p < 0.05, significantly from either neonatal iron fed plus saline group or saline plus paraquat group.