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Neurosphere size is unaffected by p75NTR expression or BDNF treatment
| p75NTR-high | p75NTR-mid | p75NTR-negative | |
|---|---|---|---|
| Control | 116.7 ± 13.5 | 128.4 ± 12.1 | 120.9 ± 10.7 |
| +BDNF | 139 ± 21.4 | 136.4 ± 14.8 | 119.0 ± 10.6 |
Primary P2 SVZ cells were sorted for p75NTR expression by flow cytometry and cultured in the presence or absence of BDNF for 7 d. The average neurosphere size (diameter; in micrometers) for each culture was then determined (mean ± SD; n = 3 experiments).
