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. 2007 Apr 4;27(14):3695–3702. doi: 10.1523/JNEUROSCI.4403-06.2007

Figure 1.

Figure 1.

Selective effects of ethanol, heroin, and cocaine self-administration on eCB levels in NAc shell microdialysates. Top, The effects of ethanol (EtOH; a), heroin (c), and cocaine (e) self-administration on dialysate AEA (open circles) and 2-AG (filled circles) levels expressed as the percentage of change from predrug baseline. Bottom, Cumulative drug intake during the self-administration sessions (b, ethanol 10% (w/v) oral intake; n = 9) (d, heroin 20 μg per infusion, i.v.; n = 7) (f, cocaine 0.25 mg per infusion, i.v.; n = 8). Error bars indicate SEM. *p < 0.05; relative to baseline.