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. 2007 Apr 4;27(14):3663–3676. doi: 10.1523/JNEUROSCI.0448-07.2007

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Copyright © 2007 Society for Neuroscience 0270-6474/07/273663-14$15.00/0

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Figure 7. — Cooperative enhancement of DSE by combined activation of M₁ and group I mGluRs. A, Representative data showing enhancement of DSE by combined application of 5 μm DHPG and 0.5 μm oxo-M. Data are shown in a manner similar to Figure 6B. Calibration: 100 pA, 10 ms. depol., Depolarizing pulse. B, Summary bar graph showing enhancement of DSE by 5 μm DHPG alone, 1 μm oxo-M alone, coapplication of 5 μm DHPG and 0.5 μm oxo-M, and coapplication of DHPG and oxo-M in the presence of 1 μm pirenzepine (Prz).