Figure 7.
The δ-GABAAR-mediated conductance modulates burst firing in dLGN thalamic relay neurons. A, B, Cell-attached recordings from a dLGN (A) and vLGN (B) relay neuron before and after THIP application. C, Raster plot of the spikes elicited in response to extracellular current injection during the recording shown in A. In the presence of 1 μm THIP, a clear increase in the latency to first spike is seen, along with an increase in the variability of this delay. However, the number of spikes and the average frequency of these bursts do not alter. D, Quantification of the change in burst latency and the change in the variability (CV) of the burst latency in dLGN and vLGN relay neurons.