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. 2007 Apr 11;27(15):4201–4209. doi: 10.1523/JNEUROSCI.3110-06.2007

Figure 3.

Figure 3.

Regulation by fluoxetine and SB271046 of phospho-Ser845-GluR1 in the frontal cortex in intact mice. Top, Immunoblots showing the levels of phospho-Ser845-GluR1 and total GluR1 in the frontal cortex 30 min after intraperitoneal administration of saline, fluoxetine (20 mg/kg), SB271046 (10 mg/kg), or SB271046 (10 mg/kg) together with fluoxetine (20 mg/kg) in mice. Bottom, The histogram shows the quantification of phospho-Ser845-GluR1 in the frontal cortex after the indicated treatments. Data represent means ± SEM for five to six mice per group. *p < 0.05 compared with saline-treated mice; #p < 0.05 compared with SB271046 (10 mg/kg) plus fluoxetine-cotreated mice; one-way ANOVA followed by Newman–Keuls test for pairwise comparisons.