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Regulation by EMDT of the phosphorylation states of DARPP-32 and GluR1 in slices of neostriatum. Dose-response experiments of in vitro regulation by EMDT of phosphorylation of Thr34-DARPP-32 (A) and Ser845-GluR1 (B) in striatal slices. Slices were incubated with EMDT (3, 10, 30, and 100 μm) for 5 min. Data represent means ± SEM (n = 6–10). *p < 0.05 compared with vehicle; one-way ANOVA followed by Newman–Keuls test.
