Figure 9.

Antidepressant-like effects of EMDT in the tail suspension test. A, Mice were injected with EMDT (1, 2.5, 5, 10, or 15 mg/kg) 30 min before the trial. B, Saline, SB271046 (10 mg/kg), EMDT (10 mg/kg), or SB271046 (10 mg/kg) combined with EMDT (10 mg/kg), 30 min before the tail suspension test trial. The trial was conducted for a period of 5 min, during which the duration of immobility was recorded. Data represent means ± SEM for eight mice per group. *p < 0.05 compared with saline; ^#p < 0.05 compared with SB271046 (10 mg/kg) plus EMDT; one-way ANOVA followed by Duncan's test.