Figure 5.

Synaptic PPD cannot be attributed specifically to NMDA or AMPA receptors. A, Blockade of NMDA receptors with 50 μm AP-5 did not block PPD of RFR at 10 s. Notice that RFR was more transient in AP-5. B, In 25 μm CNQX (blocker of AMPA receptors) and 0 Mg²⁺ Ringer's solution, the RFR was delayed and increased (NMDA receptors were relieved from Mg²⁺ blockade), but this did not block the PPD at 10 s. C, The pooled data of PPD at 10 s shows that PPD did not change under these conditions (error bars are ±SE).