AMPA receptor desensitization cannot account for glutamate puff-induced PPD at 10 s. A, The PPD of the feedback response to a 2 mm glutamate puff onto the Mb bipolar cell. B, This PPD was not blocked by 50 μm cyclothiazide. C, It was also not blocked by the presence of both 50 μm cyclothiazide and 50 μm SR95531. Traces in A–C are successively obtained traces from the same Mb-type bipolar cell terminal. D, The pooled data from five terminals are shown (error bars are ±SE; ***p < 0.001; **p < 0.01). CTZ, Cyclothiazide.