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. 2007 Jul 11;27(28):7553–7558. doi: 10.1523/JNEUROSCI.1786-07.2007

Figure 1.

Figure 1.

NMDAR-dependent LTP of sensory and ASSN synapses in olfactory cortex. A, Synaptic plasticity of LOT synapses in P5–P10 rats. A1, Recording configuration. A2, Pairing stimulation of one LOT pathway with depolarization induces LTP (filled circles), whereas the unpaired pathway (open circles) is unaffected. Traces show EPSCs from one cell before and 30 min after LTP induction at paired (left) and control (right) inputs. A3, APV prevents the induction of LTP at LOT synapses (open circles), whereas interleaved control recordings (filled circles) show robust LTP. A4, LTP of LOT synapses in A2 and A3 does not alter the paired-pulse ratio (n = 11). Traces before and 30 min after LTP induction from one cell are superimposed (left) and scaled (right). B, Synaptic plasticity of LOT and ASSN synapses in P15–P19 rats. B1, Recording configuration. B2, Pairing both LOT and ASSN inputs elicits robust LTP at ASSN synapses (open circles) and weak LTP at LOT synapses (filled circles). B3, APV blocks LTP induction at ASSN synapses. B4, LTP of ASSN synapses in B2 is not accompanied by a persistent change in the paired-pulse ratio (n = 5). Calibration: 5 ms, 100 pA. Rec, Recording; Pre, before; Post, after.