Figure 3.
dnCAV1 inhibits estradiol-induced CREB phosphorylation. A, Transfection of EGFP–dnCAV1 eliminated estradiol-induced CREB phosphorylation (F = 71.54). Estradiol attenuation of L-type calcium channel-dependent CREB phosphorylation was unaffected. B, EGFP–dnCAV1 also did not affect mGluR1a-mediated (DHPG, 50 μm) CREB phosphorylation (F = 21.77). 17βE, 17β-Estradiol.