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Interactions of PSD-95 with NR2 subunits and nNOS. A, The indicated NR C-terminal peptides were titrated at concentrations ranging from 0.001 to 100 μm against the PSD-95 PDZ domain construct indicated on the x-axis. Numbers in parentheses indicate the PDZ domain of PSD-95 in the given construct. B, Titrations of the MBP-nNOSd1 or MBP alone against the indicated PSD-95 PDZ domain construct. Bars represent the mean ± SD of quadruplicate experiments.
