Figure 2.

Traumatic brain injury causes loss of tight junction proteins. Representative Western blots and summary data for occludin (A) and claudin-5 (B) immunoreactivities after injury. Occludin was significantly decreased from 1 to 14 d after injury, whereas claudin-5 was significantly decrease at the 1 and 3 d time points. C, Quantification of Western blots indicating that 6 h postinjury administration of 5 mg/kg sulforaphane (SUL) partially preserved occludin and claudin-5 immunoreactivity at 24 h. Veh, Vehicle. Data are presented as the mean ± SEM. *p < 0.05.