Table 1.

Parameters for the flash responses of control and transgenic mouse rods

	rho+/− (n = 24)	S-opsinrho−/−(n = 20)	S-opsin-1D4rho−/−(n = 20)	S-opsinrho+/− (n = 13)	S-opsin-1D4rho+/−(n = 13)
Dark current, Id (pA)	19.1 ± 1.1	16.6 ± 1.8	15.6 ± 1.2	15.7 ± 0.9	19.1 ± 1.5
Sensitivity at λmax′ S (pA photons−1/μm2)	1.3 ± 0.2 × 10 − 1 (500 nm)	7.4 ± 1.6 × 10 − 3 (360 nm)	5.0 ± 0.5 × 10 − 3 (360 nm)	0.7 ± 0.1 × 10 − 1 (500 nm)	1.1 ± 0.1 × 10 − 1 (500 nm)
Single-photon response, a (pA)	0.56 ± 0.04	0.30 ± 0.03	0.21 ± 0.01	0.43 ± 0.07 (500 nm)	0.72 ± 0.07 (500 nm)
				0.42 ± 0.06 (360 nm)	0.77 ± 0.06 (360 nm)
Time to peak (ms)	158 ± 5	153 ± 8	155 ± 9	122 ± 5 (500 nm)	137 ± 2 (500 nm)
				122 ± 7 (360 nm)	137 ± 2 (360 nm)
Integration time (ms)	254 ± 16	221 ± 16	204 ± 17	200 ± 12 (500 nm)	224 ± 18 (500 nm)
				190 ± 14 (360 nm)	216 ± 16 (360 nm)
Normalized sensitivity at λmax, S/I d (photons−1/μm2)	6.8 ± 0.7 × 10 − 3 (500 nm)	5.1 ± 1.0 × 10 − 4 (360 nm)	3.5 ± 0.4 × 10 − 4 (360 nm)	4.2 ± 0.3 × 10 − 3 (500 nm)	5.7 ± 0.6 × 10 − 3 (500 nm)
Dark current variance (pA2)	0.11 ± 0.01 (n = 14)	0.10 ± 0.01 (n = 14)	0.08 ± 0.01 (n = 13)	0.10 ± 0.01 (n = 11)	0.11 ± 0.01 (n = 14)

Values given are mean ± SEM.