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. 2007 May 23;27(21):5812–5822. doi: 10.1523/JNEUROSCI.0491-07.2007

Figure 4.

Figure 4.

Acute BDNF antagonism does not affect mechanosensation 10 d after rhizotomy. a, Time course of mechanosensory recovery over the first 10 d after DRI. b, Time course of forepaw cold-pain development (increased response duration to an acetone squirt) in the same animals. Arrows indicate days on which intrathecal boli of IgG or TrkB-Fc were administered. c, Intrathecal boli of TrkB-Fc did not alter mechanosensory response latencies 30–90 min after administration. d, Acute BDNF antagonism reduced response durations to acetone in the same animals. Asterisks in a and b indicate significant ipsilateral (ipsi)–contralateral (contra) differences. Asterisks in c and d indicate significant differences between IgG andTrkB-Fc treatments.