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. 2007 Jan 17;27(3):616–626. doi: 10.1523/JNEUROSCI.4464-06.2007

Figure 3.

Figure 3.

Open-field locomotor activity. Altered distance moved (in centimeters) in Na,K-ATPase mice. Number of animals tested was as follows: WT, n = 36; α1+/−, n = 18; α2+/−, n = 19; α3+/−, n = 11. A, α2+/− mice tended to be hypoactive overall (inset) and were hypoactive during the first interval; α3+/− mice were hyperactive overall (inset) and during the first four intervals. No differences were noted between α1+/− and WT mice. B, Center distance (in centimeters) defined as activity more than three photobeams (3 cm) in from the side walls. α1+/− mice moved more during the first three intervals, α2+/− moved less during the first three intervals, and α3+/− mice moved more during the first four intervals in the central zone than WT. C, Margin (peripheral) distance (in centimeters) is distance moved within three photobeams of the side walls. The pattern is nearly the same as in A. D, Corner time (in seconds) is cumulative time within each interval spent interrupting one of the three photobeams closest to each corner. Inset, Total time spent in corners averaged across intervals. α1+/− and α3+/− spent less time in the corners and α2+/− spent more time in the corners than WT. Mean ± SEM; †p < 0.10, *p < 0.05, **p < 0.01, ***p < 0.001 versus WT.