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. 2019 Jul 16;7(3):e13331. doi: 10.2196/13331

Table 1.

Average accuracy for electronic case report form data entry.

Type of disease and data element NLPa only Manual group (median, IQRb) NLP-MIESc group (median, IQR) Logarithmic mean difference (95% CI) Ratio of change in geometric mean (95% CI) P value
Congenital heart disease





True-false Id 97.50 79.17 (66.74, 84.17) 96.81 (95.69, 97.29) 0.41 (0.04 to 0.79) 1.51 (1.03 to 2.20) .04

True-false IIe 92.00 95.39 (92.67, 95.89) 97.78 (97.19, 98.44) 0.21 (–0.01 to 0.10) 1.10 (0.99 to 1.24) .10

Multiple choice 89.33 82.80 (73.13, 85.83) 95.00 (94.58, 97.42) 0.29 (0.10 to 0.49) 1.34 (1.10 to 1.63) .009

Fill-in-the-blank 94.17 96.33 (95.25, 97.00) 97.00 (95.83, 97.42) 0.01 (–0.01 to 0.02) 1.01 (0.99 to 1.02) .22

Overall 92.77 90.42 (87.75, 92.68) 97.17 (96.83, 97.44) 0.14 (0.03 to 0.25) 1.15 (1.04 to 2.20) .03
Pneumonia






True-false I 88.00 70.83 (65.25, 77.75) 88.17 (87.25, 89.00) 0.30 (0.11 to 0.50) 1.35 (1.11 to 1.65) .009f

True-false II 94.44 91.25 (88.26, 93.78) 95.83 (95.21, 96.81) 0.11 (0.01 to 0.21) 1.12 (1.01 to 1.23) .04

Multiple choice 80.83 67.50 (50.21, 72.50) 81.25 (77.92, 85.00) 0.33 (0.14 to 0.52) 1.39 (1.15 to 1.68) .003f

Overall 84.15 84.21 (80.53, 86.23) 92.19 (91.49, 93.20) 0.17 (0.06 to 0.28) 1.18 (1.06 to 1.32) .008

aNLP: natural language processing.

bIQR: interquartile range.

cNLP-MIES: NLP-driven medical information extraction system.

dTrue-false I: data elements retrieved from admissions records.

eTrue-false II: data elements retrieved from imaging reports (ultrasonic cardiogram or chest x-ray).

fIndependent group t test.