The inhibitory effects of P2 receptor antagonists. a, b, The graphs show the mean effects of PPADS (100 μm), suramin (300 μm), reactive blue 2 (100 μm) (RB2), NF279 (100 μm), MRS2159 (100 μm), and NF449 (3 μm) on contractions of guinea pig isolated urinary bladder muscle strips evoked by EFS (4 Hz, 20 s; n = 4–6) (a) and ATP (300 μm; n = 4–8) (b). Error bars indicate SEM. Atropine (1 μm) and prazosin (100 nm) were present throughout.