Table 2.
Gating models of P/Q-, N-, and R-type Ca2+ channels in hippocampal MFBs
αi,0 (ms−1) | βi,0 (ms−1) | ki (mV) |
---|---|---|
P/Q-type channel model | ||
α1,0 = 5.89 | β1,0 = 14.99 | k1 = 62.61 |
α2,0 = 9.21 | β2,0 = 6.63 | k2 = 33.92 |
α3,0 = 5.20 | β3,0 = 132.80 | k3 = 135.08 |
α4,0 = 1823.18 | β4,0 = 248.58 | k4 = 20.86 |
α = 247.71 | β = 8.28 | |
N-type channel model | ||
α1,0 = 4.29 | β1,0 = 5.23 | k1 = 68.75 |
α2,0 = 5.24 | β2,0 = 6.63 | k2 = 39.53 |
α3,0 = 4.98 | β3,0 = 73.89 | k3 = 281.62 |
α4,0 = 772.63 | β4,0 = 692.18 | k4 = 18.46 |
α = 615.01 | β = 7.68 | |
R-type channel model | ||
α1,0 = 9911.36a | β1,0 = 0.62a | k1 = 67.75 |
α2,0 = 4.88 | β2,0 = 21.91 | k2 = 50.94 |
α3,0 = 4.00 | β3,0 = 51.30 | k3 = 173.29 |
α4,0 = 256.41 | β4,0 = 116.97 | k4 = 16.92 |
α = 228.83 | β = 1.78 |
aFor this step, α1,0is large, and β1,0 is small. Thus, omitting C0 and the associated transitions would only make minimal differences.