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. 2007 Dec 5;27(49):13402–13412. doi: 10.1523/JNEUROSCI.3495-07.2007

Figure 5.

Figure 5.

Rescue of tyramine and octopamine inhibition of 5-HT-dependent responses to dilute octanol in tyra-3(ok325) and f14d12.6 (ok371) null mutants. f14d12.6(ok371) or tyra-3(ok325) null mutants were rescued with the transgenes indicated below and assayed for responses to dilute octanol, as described in Materials and Methods. Either full-length f14d12.6::gfp(+) (FY745 f14 d12.6(ok371) grEx157[Pf14d12.6::f14d12.6::gfp]) or Psra-6::f14d12.6 (FY746 f14 d12.6(ok371); grEx158[Psra-6::f14d12.6]) transgenes rescued the OA inhibition of 5-HT-dependent responses to dilute octanol in f14d12.7(ok371) null animals. Similarly, a full-length tyra-3 transgene, tyra-3(+) (FY747 tyra-3(ok325) grEx159[Ptyra-3::tyra-3]) rescued the TA inhibition of 5-HT-dependent responses to dilute octanol. Data are presented as mean ± SE and analyzed by a two-tailed Student's t test. ***p < 0.001, significantly different from wild-type animals under identical incubation conditions. The number of trials is indicated under each bar.