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Scatchard analysis of [3H]-PIB binding to synthetic fibrils and human brain homogenates
| Kd1 | Bmax1 | Kd2 | Bmax2 | |
|---|---|---|---|---|
| Aβ1–42 fibrils | 0.71 | 1.01 | 19.80 | 8.34 |
| α-Synuclein fibrils | 10.07 | 2.87 | 88.49 | 9.54 |
| AD brain homogenate | 3.77 | 9254 | — | — |
| DLB-Aβ brain homogenate | 5.00 | 13,494 | — | — |
| Pure DLB brain homogenate | — | — | — | — |
| AC brain homogenate | — | — | — | — |
Units: Kd, nm; Bmax, pmol of [3H]-PIB/nmol of fibrils or pmol of [3H]-PIB/g of wet tissue.
