Table 4.

Image quantification of AD, DLB-Aβ, and age-matched control subjects

Subject group	Region	Plaque area	Lewy body area
AD (n = 12)	Frontal	4.45 ± 0.03
	Temp/Hipp	3.25 ± 0.01
DLB (n = 5)	Frontal	2.14 ± 0.02	0.06 ± 0.0003
	Temp/Hipp	1.77 ± 0.01	0.06 ± 0.0005
AC (n = 13)	Frontal	0.62 ± 0.01
	Temp/Hipp	0.68 ± 0.01

Frontal and temporal/hippocampus (Temp/Hipp) regions (Brodmann areas 9 and 20/28, respectively) from 30 subjects were evaluated. From each subject, five brain regions were examined. For image analysis, 300 high-resolution images were generated and digitized, identifying either Aβ plaques or Lewy bodies as the region of interest (ROI). The ROIs (Aβ plaques or Lewy bodies) are represented as a percentage of the total area examined.