Figure 7.

ATP potentiation of frequency is not affected by the pH of the aCSF. A, ∫XII and ∫preBötC recordings illustrating the effects on inspiratory-related output in a single slice of locally applying ATP (0.05 mm) to the preBötC at pH 7.45 ± 0.01 (5% CO₂) and pH 7.04 ± 0.02 (10% CO₂/low HCO₃⁻). B, Histogram of group data illustrating the maximum frequency response evoked by locally applying ATP (0.1 and 0.05 mm) under conditions of high (5% CO₂) and low (10% CO₂/low HCO₃⁻) extracellular pH. Error bars indicate SEM. Rel. Freq., Relative frequency.